publications

Selected Publications

See a complete list here

  1. Peña-Chilet M, Roldán G, Perez-Florido J, Ortuño FM, Carmona R, Aquino V, Lopez-Lopez D, Loucera C, Fernandez-Rueda JL, Gallego A, García-Garcia F, González-Neira A, Pita G, Núñez-Torres R, Santoyo-López J, Ayuso C, Minguez P, Avila-Fernandez A, Corton M, Moreno-Pelayo MÁ, Morin M, Gallego-Martinez A, Lopez-Escamez JA, Borrego S, Antiñolo G, Amigo J, Salgado-Garrido J, Pasalodos-Sanchez S, Morte B; Spanish Exome Crowdsourcing Consortium, Carracedo Á, Alonso Á, Dopazo J. CSVS, a crowdsourcing database of the Spanish population genetic variability. 2020; Nucleic Acids Res.; gkaa794. doi: 10.1093/nar/gkaa794.

  2. García M, López-Fernández L, Mínguez P, Morón-López S, Restrepo C, Navarrete-Muñoz MA, López-Bernaldo JC, Benguría A, García MI, Cabello A, Fernández-Guerrero M, De la Hera FJ, Estrada V, Barros C, Martínez-Picado J, Górgolas M, Benito JM, Rallón N. Transcriptional signature of resting-memory CD4 T cells differentiates spontaneous from treatment-induced HIV control. 2020; J Mol Med (Berl); 98, 1093–1105.

  3. Martínez-López D, Roldan-Montero R, García-Marqués F, Nuñez E, Jorge I, Camafeita E, Minguez P, Rodriguez de Cordoba S, López-Melgar B, Lara-Pezzi E, Fernández-Ortiz A, Ibáñez B, Valdivielso JM, Fuster V, Michel JB, Blanco-Colio LM, Vázquez J and Martin-Ventura JL. Complement C5 Protein as a Marker of Subclinical Atherosclerosis. 2020; Journal of the American College of Cardiology; 75:16 1926-1941

  4. Del Puerto-Nevado L*#, Minguez P*#, Garcia-Foncillas J. Bioinformática, inteligencia artificial y sistemas cognitivos en medicina. Colección de Bioética y Derecho Sanitario Fundación Merck. 2020; Monografía 25, in press.

  5. Heili-Frades S#, Minguez P#, Mahillo-Fernández I , Jiménez Hiscock L, Santos A, Heili-Frades D, Carballosa de Miguel MP, Fernández Ormaechea I, Álvarez Suárez L, Naya prieto A, González Mangado N, Peces-Barba Romero G. Patient Management Assisted By A Neural Network Reduces Mortatlity In An Intermediate Care Unit. Archivos de Bronconeumologia. 2019; pii: S0300-2896(19)30594-0 [PubMed] [Arch Bronconeumol.]

  6. Méndez-Barbero N, Gutierrez-Muñoz C, Madrigal-Matute J, Minguez P, Egido J, Michel JB, Martín-Ventura JL, Esteban V, Blanco-Colio LM. A major role of TWEAK/Fn14 axis as a therapeutic target for post-angioplasty restenosis. EBioMedicine. 2019;46:274-289 [PubMed]

  7. Del Puerto-Nevado L, Santiago-Hernandez A, Solanes-Casado S, Gonzalez N, Ricote M, Corton M, Prieto I, Mas S, Sanz AB, Aguilera O, Gomez-Guerrero C, Ayuso C, Ortiz A, Rojo F, Egido J, Garcia-Foncillas J, Minguez P#, Alvarez-Llamas G#. Diabetes-mediated promotion of colon mucosa carcinogenesis is associated with mitochondrial dysfunction. Mol Oncol. 2019; doi: 10.1002/1878-0261.12531. [Pubmed] [Mol Onco]

  8. Martin-Lorenzo M, Martinez PJ, Baldan-Martin M, Lopez JA, Minguez P, Santiago-Hernandez A, Vazquez J, Segura J, Ruiz-Hurtado G, Vivanco F, Barderas MG, Ruilope LM, Alvarez-Llamas G. Urine Haptoglobin and Haptoglobin-Related Protein Predict Response to Spironolactone in Patients With Resistant Hypertension. Hypertension. 2019; 73(4):794-802 [Pubmed] [Hypertension]

  9. Del Puerto-Nevado L*, Minguez P*#, Corton M, Solanes-Casado S, Prieto I, Mas S, Sanz AB, Gonzalez-Alonso P, Villaverde C, Portal-Nuñez S, Aguilera O, Gomez-Guerrero C, Esbrit P, Vivanco F, Gonzalez N, Ayuso C, Ortiz A, Rojo F, Egido J, Alvarez-Llamas G#, Garcia-Foncillas J on behalf of the DiabetesCancerConnect Consortium. Molecular evidence of field cancerization initiated by diabetes in colon cancer patients. Molecular Oncology. 2019; 13(4):857-872 [PubMed] [Mol Onco]

  10. Rodrigo-Muñoz JM, Cañas JA, Sastre B, Rego N, Greif G, Rial M, Minguez P, Mahíllo-Fernández I, Fernández-Nieto M, Mora I, Barranco P, Quirce S, Sastre J, Del Pozo V. Asthma diagnosis using integrated analysis of eosinophil microRNAs. Allergy. 2019; 74(3):507-517 [PubMed]

  11. Martin-Merida I, Aguilera-Garcia D, Fernandez-San Jose P, Blanco-Kelly F, Zurita O, Almoguera B, Garcia-Sandoval B, Avila-Fernandez A, Arteche A, Minguez P, Carballo M, Corton M, Ayuso C. Toward the Mutational Landscape of Autosomal Dominant Retinitis Pigmentosa: A Comprehensive Analysis of 258 Spanish Families. Investigative ophthalmology & visual science. 2018; 59(6):2345-2354. [PubMed]

  12. Sanchez-Navarro I, R J da Silva L, Blanco-Kelly F, Zurita O, Sanchez-Bolivar N, Villaverde C, Lopez-Molina MI, Garcia-Sandoval B, Tahsin-Swafiri S, Minguez P, Riveiro-Alvarez R, Lorda I, Sanchez-Alcudia R, Perez-Carro R, Valverde D, Liu Y, Tian L, Hakonarson H, Avila-Fernandez A, Corton M, Ayuso C. Combining targeted panel-based resequencing and copy-number variation analysis for the diagnosis of inherited syndromic retinopathies and associated ciliopathies. Scientific reports. 2018; 8(1):5285. [PubMed]

  13. Minguez P, Bork P. Bioinformatics Analysis of Functional Associations of PTMs. Methods in molecular biology (Clifton, N.J.). 2017; 1558:303-320. [PubMed]

  14. Yu-Wei S, Minguez P, Bork P, Auburger JJ, Guilbride DL, Kramer G and Bukau B. "Operon structure and cotranslational subunit association direct protein assembly in bacteria" Science. 2015; DOI: 10.1126/science.aac8171 [Pubmed] [Science]

  15. Minguez P, Ivica L, Parca L, Garcia-Alonso L, Dopazo J, Huerta-Cepas J, Bork P. "PTMcode v2: a resource for functional associations of post-translational modifications within and between proteins" Nucl. Acids Res.2014; 1 doi: 10.1093/nar/gku1081 [Pubmed] [NAR] [pdf]

  16. Minguez P*, Ivica L*, Parca L, Bork P. "PTMcode: a database of known and predicted functional associations between post-translational modifications in proteins." Nucl. Acids Res. 2013;41(Database issue):D306-11 [Pubmed] [NAR] [pdf]

  17. Franceschini A, Szklarczyk D, Frankild S, Kuhn M, Simonovic M, Roth A, Lin J, Minguez P, Bork P, von Mering C, Jensen LJ. STRING v9.1: protein-protein interaction networks, with increased coverage and integration. Nucleic acids research. 2013; 41(Database issue):D808-15 [PubMed]

  18. Minguez P, Parca L, Diella F, Mende DR, Kumar R, Helmer-Citterich M, Gavin AC, van Noort V, Bork P. "Deciphering a global network of functionally associated post-translational modifications" Molecular Systems Biology.2012; 8:599. [Pubmed] [MSB] [pdf] [Supplementary material]

  19. Minguez P, Dopazo J. "Assessing the biological significance of gene expression signatures and co-expression modules by studying their network properties" PLoS One. 2011; 6(3): e17474. [Pubmed] [PLoSOne] [pdf]

  20. Szklarczyk D, Franceschini A, Kuhn M, Simonovic M, Roth A, Minguez P, Doerks T, Stark M, Muller J, Bork P, Jensen LJ, von Mering C. The STRING database in 2011: functional interaction networks of proteins, globally integrated and scored. Nucleic acids research. 2011; 39(Database issue):D561-8 [PubMed]

  21. Al-Shahrour F, Minguez P, Marques-Bonet T, Gazave E, Navarro A and Dopazo J. "Selection upon genome architecture: conservation of functional neighborhoods with changing genes" PLoS Computational Biology. 2010;6(10):e1000953. [PubMed] [PLoS CB]

  22. Minguez P, Dopazo J. "Functional genomics and networks: new approaches in the extraction of complex gene modules." Expert Rev Proteomics. 2010;7(1):55-63. [PubMed] [pdf]

  23. Minguez P, Gotz S, Montaner D, Al-Shahrour F, Dopazo J. "SNOW, a web-based tool for the statistical analysis of protein-protein interaction networks." Nucl. Acids Res. 2009;37:W109-114. [PubMed] [pdf]

  24. Minguez P, Dopazo J. "Protein Interactions for Functional Genomics." In: Li X-L, Ng S-K, eds. Biological Data Mining in Protein Interaction Networks. Hershey, USA: Idea Group Inc (IGI); 2009. [Google Books] [pdf]

  25. Horcajadas JA, Minguez P, Dopazo J, et al. "Controlled ovarian stimulation induces a functional genomic delay of the endometrium with potential clinical implications." J Clin Endocrinol Metab. 2008;93:4500-10. [PubMed] [pdf]

  26. Minguez P, Al-Shahrour F, Montaner D, Dopazo J. "Functional profiling of microarray experiments using text-mining derived bioentities." Bioinformatics. 2007;23:3098-9. [PubMed] [pdf]

  27. Minguez P, Al-Shahrour F, Dopazo J. "A function-centric approach to the biological interpretation of microarray time-series." Genome Inform. 2006;17:57-66 [PubMed] [pdf] [Sup mat.]

  28. Al-Shahrour F, Minguez P, Tarraga J, et al. "BABELOMICS: a systems biology perspective in the functional annotation of genome-scale experiments." Nucleic Acids Res. 2006;34:W472-6. [PubMed]